Tadalista 20 mg, which contains Tadalafil. It usually occurs because Tadalafil relaxes blood vessels and smooth muscles throughout the body, not just in the *****. This can affect muscles in the lower back and pelvic region, sometimes causing discomfort. When it can happen: Within a few hours after taking the medication – usually 12–24 hours after ingestion, though timing varies. With higher doses or first-time use – men who are new to Tadalafil or who take a dose higher than needed may notice muscle aches or back pain. During prolonged erections or ***** activity – physical exertion may contribute to temporary muscle soreness. Typical pattern: Mild to moderate, dull pain in the lower back. Usually resolves within 24–48 hours without treatment. Over-the-counter pain relievers (like paracetamol or ibuprofen) can help if needed. Red flag: If back pain is severe, persistent, or accompanied by chest pain, dizziness, or vision changes, seek immediate medical attention.